Acute promyelocytic leukemia associated with hypofibrinogenemia.
نویسنده
چکیده
APROMYELOCYTOID” bone marrow and disturbances in fibrinogen are prominent features of a form of leukemia which is characterized by a rapid course, severe hemorrhage and poor response to therapy. This study is based upon 17 patients observed over the past 9 years. The first seven patients in this series were the basis of a brief report’ in 1955 of the occurrence of hypofibrinogenemia in acute leukemia associated with a promyelocytic bone marrow. The appearance of several reports of similar patients in the literature2#{176} merits emphasis of promyelocytic fibrinopathic leukemia as a distinct syndrome.
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عنوان ژورنال:
- Blood
دوره 21 شماره
صفحات -
تاریخ انتشار 1963